Polynucleotides: a new anti-aging technology

Under the terms PDRN (polymerized polynucleotides) and PN-HPT™ (Polynucleotide - Highly Purified Technology) hides a new technology at the service of aesthetic medicine.

These are resorbable gels based on polynucleotides, i.e. highly purified DNA fragments of natural origin which are the result of 70 years of research.

The action of the polynucleotide chain is:



The biochemical properties of high molecular weight polynucleotides have many positive effects on the skin:


Antioxidant effect

Polynucleotides have the ability to trap free radicals, amplifying the protection and regeneration activity of the skin.



The structure of the polynucleotides makes it possible to retain water molecules, intensely moisturizing the tissues. The intradermal spaces are filled, making the tissues firmer and more hydrated.


Growth of fibroblasts

The intense hydration associated with antioxidant activity creates an optimal physiological environment to stimulate the metabolic activity of fibroblasts as well as their regeneration, boosting the production of collagen and elastin. This ideal environment for the growth of fibroblasts, thus improves the elasticity of tissues.

The products using this technology are the Juvenus and the Plinest

The JUVENUS range:



The PLINEST® range


For Face Neck Decolleté




The PLINEST® range is reinforced by the NEWEST® range combining


Thanks to the combination of these 3 essential ingredients, you get a better skin bio-revitalization treatment.

The treatment protocol

To obtain optimal results, the treatment protocol is as follows: 3 to 4 sessions at intervals of 3 to 4 weeks, once a year.

Protocol to be repeated once a year according to the patient's needs. The interval between each treatment depends on various factors such as the quality of the skin, lifestyle, physical exercise, exposure to the sun or UV lamps, age.

Polynucleotides injections: a new anti-aging technology