Carboxytherapy has been used since 1930 to treat pathologies of vascular origin (scarring of leg ulcers, etc.) and for about twenty years in the context of aesthetic tissue regeneration. Indeed, the injection of medical carbon dioxide (CO²) increases tissue oxygenation (Bohr effect). The result is improved cell metabolism in the treated areas, skin elasticity and rejuvenation of the dermis and epidermis.

Analysis of the skin before and after administration of carbon dioxide shows:



Carboxytherapy can be practiced alone or in combination with all other aesthetic medicine techniques.


The considerable increase in oxygenation of the treated tissues has many beneficial effects:



Skin slackening and skin rejuvenation

Carboxytherapy is an anti-ageing treatment that plumps up and densifies the dermis on wrinkled skin. The skin becomes more elastic, more toned and velvety, younger and healthier. We have a real skin rejuvenation
Combined with mesotherapy, it potentiates the effects of the injection.

Targeted locations for the treatment of sagging skin:


Problems combining sagging skin associated with a small fat overload can benefit from both the stimulation of collagen fibers and the destruction of fat cells. For example in the treatment of the oval of the face with fat chin, or a wrinkled and slightly fatty belly.

Stretch marks

Stretch marks are linked to the lack of sufficient production of collagen and elastin by the fibroblasts during a rapid change in skin tension.

The patients concerned are women or men who have experienced a rapid change in their weight, and women who have experienced pregnancy, hormonal imbalance or treatment with corticosteroids.

A "crack" appears in the elasticity of the skin which is thinned and forms a stretch mark. Initially purplish red at first they become pearly and deeper with time.

Carboxytherapy is effective in treating stretch marks. The most recent, pink in color, are virtually eliminated. The older ones, white in color, fades with more elastic and toned skin. We obtain a tightening of the stretch marks which present a crumpled aspect. If the stretch marks have not completely disappeared after the treatment, they will be less visible, and the appearance of the treated areas will be improved. When the stretch mark has disappeared or is very faded, the result is final. There is no need for booster sessions.


The areas treated are:


Surgical or acne scars

Carboxytherapy revascularizes scarred areas, increasing the synthesis of collagen and elastin fibers. The result is a progressive improvement of the scar. The combination of PRP or i-Prf allows the contribution of growth factors to potentiate the process.

Venous insufficiency

The effects on the microcirculation is represented by active vasodilation with a marked improvement in venous and arterial circulation. It is an effective preventive and curative therapy for arterial, venous and capillary circulation problems. Improves heavy legs and restless leg syndrome.

Treatment of alopecia

Carboxytherapy is used to combat hair loss by improving circulation and oxygenation of the tissues that nourish the follicles. The vasodilation effect created by CO2 injections potentiates the effects of peptide mesotherapy or PRP or i-PRF when combining treatments. This brings more vitamins and nutrients to the follicles, promoting growth and stabilizing hair loss.

Slimming and Body shaping

Carboxytherapy acts on moderate fatty deposits. The pressure of CO2 allows the destruction of part of the fat cells by rupture of the cell membranes (lipolisis). The loss of volume being moderate, the combination with a HIFU treatment, such as the Ultraformer III, potentiates the results.

The main indications are:



Activation of cellular metabolism promotes the destocking of fat, promotes lymphatic drainage and reduces diffuse cellulite with a reduction in dimples of orange peel skin to obtain smoother skin.


There are almost no contraindications to carboxytherapy, except for pregnant women as a precautionary principle.


The treatment consists of localized micro-injections of small quantities of medical carbon dioxide subcutaneously and intradermally. We use the latest generation CARBO2 HP machine, which is painless since a computer electronically regulates the pressure, the temperature (the gas is heated), the volume of the injection, and the speed of the flow. This is not the case with CONCERTO type pistols.

The doctor injects the carbon dioxide under the skin using a small, very fine needle inserted into a sterile single-use tube. This technique is risk-free because CO² is naturally produced by our body and reabsorbed by our tissues and then eliminated by the lungs.

The treatment is completely painless and therefore requires no anesthesia.
Depending on the desired effects, CO2 can be injected into the dermis or into the hypodermis. The amount of gas to inject depends on the area to be treated and the imperfections to be removed.
Carbon dioxide is first absorbed by skin tissue and then converted into oxygen by red blood cells. During the treatment, the patient may feel a slight local pain and a slight crackling under the skin which will disappear in a few minutes.

The patient may experience slight itching and redness, but within few minutes the tissues returned to a normal appearance, there are no bruises or swelling.


A session lasts between ten and twenty minutes.

A complete treatment includes:



We do two sessions the first week, then one session per week. It is advisable to renew the treatment in general for 3 sessions, once or twice a year to maintain the results over the long term. But some indications such as stretch marks do not require booster sessions.


The patient may feel a slight itch and have redness for one to two hours, there are no bruises or edema.
There is no social exclusion.

The treatment poses no danger to the patient. Carboxytherapy can be defined as a natural medicine, since it acts as a powerful vasodilator and works physiologically by regulating the function of microcirculation.


Results are visible from the second session and continues to improve during the treatment, and in the following three months because of the reaction time of the fibroblast is 90 days on average.

Carboxytherapy (esthetical) in Monaco - Dr Antoni